Curriculum Vitae – Prof. Dr. med. Hubert Löwenheim

General information


Current Position: Professor and Chair, Dept. of Otolaryngology - Head & Neck Surgery, University of Tübingen Medical Center

Current Institution:
Eberhard-Karls-Universität Tübingen (EKUT)
Dept of Otolaryngology, Head and Neck Surgery (OHNS)

Elfriede-Aulhorn-Str. 5, 72076 Tübingen, DE

ORCID: 0000-0001-8200-8804

Pubmed

Qualifications and Career

Degree:

1997: German Board of Otorhinolaryngology, State Chamber of Physicians, Stuttgart, DE
1995: Doctorate, Auditory Physiology, Supervisor: Prof. Klinke, University of Frankfurt, DE
1992-1997: Resident, University of Tübingen Medical School, DE

Stages of academic/professional carrer:

Since 2016: Professor and Chair Department Otolaryngology- Head & Neck Surgery, Tübingen University Medical center, DE
2014-2016: Professor and Chair, Department Otolaryngology- Head & Neck Surgery, Oldenburg University Medical School, DE
2009-2014: Assoc. Professor and Deputy Chair, Department Otolaryngology- Head & Neck Surgery, Tübingen University Medical center, DE
2006-2014: Consultant in Charge
2006: Habilitation Otorhinolaryngology, University of Tübingen, Prof. Dr. H.P. Zenner
1997-2009: Senior Physician (Oberarzt)
1998: Visiting Research Fellow - Virginia Merrill Boedell Hearing Research Center, University of Washington - Seattle, USA
1997: Visiting Researcher, Dept of Neuroscience and Communication, University of Keele, UK
1993: Visiting Researcher, Dept of Neuroscience, University of Virginia, Charlottesville, USA
1992-1997: Internship/Assistant Doctor, Department Otolaryngology- Head & Neck Surgery, Tübingen University Medical Center, DE

Activities in the Research System

Clinical studies:

  • Main investigator: BEMED - Double-blind, placebo-controlled clinical trial “Therapy of Menière's disease with betahistine” (DSGZ, German Dizziness and Balance Center)
  • Main investigator: Application observation “Vibroplasty Couplers” (Sponsor: Vibrant MedEl, Innsbruck, Austria)
  • Main investigator: BETAVEST - double-blind, placebo-controlled clinical trial “Effects of betahistine on central vestibular compensation in acute unilateral vestibulopathy” (DSGZ, German Dizziness and Balance Center)
  • Main investigator: PROVEMIG - double-blind, placebo-controlled clinical trial “Prophylactic treatment of vestibular migraine with metoprolol” (DSGZ, German Dizziness and Balance Center)

10 selected publications

  1. Tropitzsch A, Schade-Mann T, Gamerdinger P, Dofek S, Schulte B, Schulze M, Fehr S, Biskup S, Haack TB, Stöbe P, Heyd A, Jennifer Harre J, Lesinski-Schiedat A, Büchner A, Lenarz T, Warnecke A, Müller M, Vona B, Dalhoff E, Löwenheim H, Holderried M (2023) Variability in Cochlear Implantation Outcomes in a Large German Cohort with a Genetic Etiology of Hearing Loss. Ear Hear. 44(6):1464-1484 DOI:10.1097/AUD.0000000000001386 (conceptualization, recruitment of the families, data curation, clinical data interpretation, writing)
  2. Guntinas-Lichius O, Arnold D, Volk GF, Korth D, Aschenbach R, Hempel JM, Schneider F, Schade-Mann T, Gamerdinger P, Tropitzsch A, Löwenheim H (2022) Accessing the stapedius muscle via novel surgical retrofacial approach during cochlear implantation surgery: Intraoperative results on feasibility and safety. PLoS One. 17(8):e0272943. DOI: 10.1371/journal.pone.0272943 Open Access (conceptualization, project administration, resources, validation, writing – review & editing)
  3. Peixoto Pinheiro B, Müller M, Bös M, Guezguez J, Burnet M, Tornincasa M, Rizzetto R, Rolland JF, Liberati C, Lohmer S, Adel Y, Löwenheim H (2022) A potassium channel agonist protects hearing function and promotes outer hair cell survival in a mouse model for age-related hearing loss. Cell Death Dis. 13(7):595. DOI:10.1038/s41419-022-04915-5 Open Access (conceptualization, supervision, interpretation, writing)
  4. Trpchevska N, (> 30 authors…), Löwenheim H, (>20 authors…), Cederroth CR, Williams FMK, Nagtegaal AP (2022) Genome-wide association meta-analysis identifies 48 risk variants and highlights the role of the stria vascularis in hearing loss. Am J Hum Genet. 109(6):1077-1091. DOI:10.1016/j.ajhg.2022.04.010 Open Access (contributed to cohort-specific data collection, analysis)
  5. Tropitzsch A, Schade-Mann T, Gamerdinger P, Dofek S, Schulte B, Schulze M, Battke F, Fehr S, Biskup S, Heyd A, Müller M, Löwenheim H, Vona B, Holderried M (2022) Diagnostic yield of targeted hearing loss gene panel sequencing in a large german cohort with a balanced age distribution from a single diagnostic center: an eight-year study. Ear Hear. 43(3):1049-1066. DOI:10.1097/AUD.0000000000001159 (contributed to the sutdy conception, recruitment of the failies, data curation, clinical data interpretation, writing)
  6. Peixoto Pinheiro B, Adel Y, Knipper M, Müller M, Löwenheim H (2021) Auditory Threshold Variability in the SAMP8 Mouse Model of Age-Related Hearing Loss: Functional Loss and Phenotypic Change Precede Outer Hair Cell Loss. Front Aging Neurosci. 13:708190. DOI: 10.3389/fnagi.2021.708190 Open Access (conceptualization, supervision, interpretation, writing)
  7. Rousset F, Kokje VBC, Sipione R, Schmidbauer D, Nacher-Soler G, Ilmjärv S, Coelho M, Fink S, Voruz F, El Chemaly A, Marteyn A, *Löwenheim H*, Krause KH, Müller M, Glückert R, Senn P (2020) Intrinsically self-renewing neuroprogenitors from the A/J mouse spiral ganglion as virtually unlimited source of mature auditory neurons. Front Cell Neurosci. 14:395. DOI:10.3389/fncel.2020.599152 Open Access (funding acquisition, writing)
  8. Rad A, Schade-Mann T, Gamerdinger P, Yanus GA, Schulte B, Müller M, Imyanitov EN, Biskup S, Löwenheim H, Tropitzsch A, Vona B (2021) Aberrant COL11A1 splicing causes prelingual autosomal dominant nonsyndromic hearing loss in the DFNA37 locus. Hum Mutat. 42(1):25-30. DOI:10.1002/humu.24136 Open Access (study conception, recruitment of the families, data curation and clinical data interpretation)
  9. Braun K, Walker K, Sürth W, Löwenheim H, Tropitzsch A (2019) Triphasic pulses in cochlear implant patients with facial nerve stimulation. Otol Neurotol. 40(10):1268-1277. DOI: 10.1097/MAO.0000000000002398 (study conception, clinical data interpretation, writing)
  10. Kramer B, Tropitzsch A, Müller M, Löwenheim H (2017) Myelin-induced inhibition in a spiral ganglion organ culture - Approaching a natural environment in vitro. Neuroscience. 357: 75-83. DOI:10.1016/j.neuroscience.2017.05.053 (study design, writing)


   
   
Last modified: 02.11.2023 14:36