Curriculum Vitae – Apl. Prof. Dr. rer. nat. Lukas Rüttiger

General information


Current Position: Apl. Professor, Research Scientist

Current Institution:
Eberhard-Karls-Universität Tübingen (EKUT)
Dept of Otolaryngology, Head and Neck Surgery (OHNS)
Molecular Physiology of Hearing
Elfriede-Aulhorn-Str. 5, 72076 Tübingen, DE

ORCID: 0000-0003-0015-0714

Pubmed

Qualifications and Career

Degree:

1984-1991: Biology, University of Tübingen, DE
1995: Doctorate, Biology, „Der zeitliche Auflösungsbereich des visuellen Systems und seine Bedeutung für die Farbdiskrimination“Supervision of Prof. Dr. Schmidt-Koenig und Prof. Dr. Zenner, University of Tübingen, DE

Stages of academic/professional carrer:

Since 2018 : Academic degree of „außerplanmäßiger Professor“ University of Tübingen, Tübingen, DE Hearing Research Centre, Molecular Physiology of Hearing
Since 2013 : Private Lecturer (associate professor level) at the University of Tübingen, DE
2013 Neurosensory systems “Systemneurobiologie gestörter Hörwahrnehmung (Lärm bedingte Hörstörungen und Tinnitus)”, University of Tübingen, Department of Otolaryngology, Head and Neck Surgery, Prof. Dr. Dr. H.P. Zenner
Since 2009 : Permanent position as senior scientist, tenure
Since 2000 : Scientific assistant at the University Tübingen, Dept. of Otolaryngology, Head and Neck Surgery (Prof. Dr. med. Dr. h.c. H.-P. Zenner), Hearing Research Centre, Molecular Physiology of Hearing (Prof. Dr. M. Knipper)
1996-2000 : Scientific assistant, Max-Planck-Institute for Biophysical Chemistry in Göttingen (DE), Department Neurobiology and Membrane Physics (Prof. Dr. E. Neher), workgroup Primate Retina and Colour Vision (Prof. Dr. B.B. Lee, PhD), DE
1995-1996 : Postdoctoral position, Department for Experimental Ophthalmology at the University Eye Hospital in Tübingen with Prof. Dr. phil. L.T. Sharpe

Activities in the Research System

Project coordination, membership in joint projects

Teaching

Awards and conferred memberships

10 selected publications

  1. Calis D, Hess M, Marchetta P, Singer W, Modro J, Nelissen E, Prickaerts J, Sandner P, Lukowski R, Ruth P, Knipper M, Rüttiger L (2023) Acute deletion of the central MR/GR steroid receptor correlates with changes in LTP, auditory neural gain, and GC-A cGMP signaling. Front Mol Neurosci. 16:1017761. DOI:10.3389/fnmol.2023.1017761 Open Access (conceptualization, funding, animal application, methodology, data collection, data analysis, software, writing – original draft and review and revision, supervision)
  2. Marchetta P, Eckert P, Lukowski R, Ruth P, Singer W, Rüttiger L, Knipper M (2022) Loss of central mineralocorticoid or glucocorticoid receptors impacts auditory nerve processing in the cochlea. iScience. 25(3):103981. DOI:10.1016/j.isci.2022.103981 Open Access (conceptualization, funding, animal application, methodology, data collection, data analysis, software, writing – original draft and review and revision, supervision)
  3. Hofmeier B, Wertz J, Refat F, Hinrichs P, Saemisch J, Singer W, Rüttiger L, Klose U, Knipper M, Wolpert S (2021) Functional biomarkers that distinguish between tinnitus with and without hyperacusis. Clin Transl Med. 11(5):e378. DOI:10.1002/ctm2.378 (research design, data analysis, writing- editing and review, supervision)
  4. Jeng JY, Harasztosi C, Carlton AJ, Corns LF, Marchetta P, Johnson SL, Goodyear RJ, Legan KP, Rüttiger L, Richardson GP, Marcotti W (2021) MET currents and otoacoustic emissions from mice with a detached tectorial membrane indicate the extracellular matrix regulates Ca2+ near stereocilia. J Physiol. 599(7):2015-2036. DOI:10.1113/JP280905 Open Access (conceptualization, data collection and analysis, writing – original draft and review, supervision)
  5. Marchetta P, Möhrle D, Eckert P, Reimann K, Wolter S, Tolone A, Lang I, Wolters M, Feil R, Engel J, Paquet-Durand F, Kuhn M, Knipper M, Rüttiger L (2020) Guanylyl Cyclase A/cGMP Signaling Slows Hidden, Age- and Acoustic Trauma-Induced Hearing Loss. Front Aging Neurosci. 12:83. DOI:10.3389/fnagi.2020.00083 (conceptualization, funding, animal application, writing – original draft, writing- review and editing, supervision)
  6. Möhrle D, Hofmeier B, Amend M, Wolpert S, Ni K, Bing D, Klose U, Pichler B, Knipper M, Rüttiger L (2019) Enhanced Central Neural Gain Compensates Acoustic Trauma-induced Cochlear Impairment, but Unlikely Correlates with Tinnitus and Hyperacusis. Neuroscience. 407:146-169. DOI:10.1016/j.neuroscience.2018.12.038 (conceptualization, supervision, writing – original draft, writing- review and editing)
  7. Alavi M, Bette S, Schimpf S, Schuettauf F, Schraermeyer U, Wehrl HF, Rüttiger L, Beck SC, Tonagel F, Pichler BJ, Knipper M, Peters T, Laufs J & Wissinger B (2007) A splice site mutation in the murine Opa1 gene features pathology of autosomal dominant optic atrophy. Brain. 130(Pt4):1029-1042. DOI:10.1093/brain/awm005 (conceptualization, animal application, methodology, data collection, data analysis, writing – original draft)
  8. Rüttiger L, Sausbier M, Zimmermann U, Winter H, Braig C, Engel J, Knirsch M, Arntz C, Langer P, Hirt B, Müller M, Köpschall I, Pfister M, Münkner S, Rohbock K, Pfaff I, Rüsch A, Ruth P, Knipper M (2004) Deletion of the Ca2+-activated potassium (BK) α-subunit but not the BKβ1-subunit leads to progressive hearing loss. Proc Natl Acad Sci USA. 101(35):12922-12927. DOI:10.1073/pnas.0402660101 Open Access (methodology, data collection, data analysis, software, writing – original draft and revision, supervision)
  9. Martin PR, Lee BB, White AJ, Solomon SG, Rüttiger L (2001) Chromatic sensitivity of ganglion cells in the peripheral primate retina. Nature. 410(6831):933-936. DOI: 10.1038/35073587 (data collection and analysis, writing – original draft)
  10. Rüttiger L, Braun DI, Gegenfurtner KR, Petersen D, Schönle P, Sharpe LT (1999) Selective color constancy deficits after circumscribed unilateral brain lesions. J Neurosci. 19(8):3094-3106. DOI:10.1523/JNEUROSCI.19-08-03094.1999 Open Access (data collection and analysis, writing – original draft)