Curriculum Vitae – Prof. Dr. rer. nat. Marlies Knipper

General information

Current Position: W3 Professor, Group Leader

Current Institution:
Eberhard-Karls-Universität Tübingen (EKUT)
Dept of Otolaryngology, Head and Neck Surgery (OHNS)
Molecular Physiology of Hearing
Elfriede-Aulhorn-Str. 5, 72076 Tübingen, DE

ORCID: 0000-0002-6181-5735

Pubmed

Qualifications and Career

Degree:

1976-1985: BiologyUniversity of Osnabrück, DE
1987: Doctorate, Biology, “The high-affinity choline transport system: studies with synaptosome isolations from Locusta migratoria” under the supervision of Prof. Dr. Heinz Breer, University of Osnabrück, DE

Stages of academic/professional carrer:

Since 2008: Full Professorship in “Molecular Physiology of Hearing” at the University of Tübingen, DE
2004-2008: Academic degree “Außerplanmäßiger Professor” at the Tübingen Hearing Research Centre, University of Tübingen, DE
1997: Habilitation Molecular Neurobiology - “The epigenetic regulation of central nervous, cellular and morphogenetic processes in the inner ear before the onset of cochlear function”, University of Tübingen, Department of Otolaryngology, Head and Neck Surgery (Prof. Dr. Dr. H.P. Zenner)
1993-2004: Assistant Professor, Head of “Molecular Neurobiology of Hearing”, Dept. of Otolaryngology, Head and Neck Surgery, University of Tübingen, DE
1992-1993: Fellowship, University of Western Ontario, London, CA
1987-1992: Assistant Professor, Institute of Physiology, University of Stuttgart-Hohenheim, DE
1991: Fellowship, University of Worcester, Boston, MA, USA
1990: Fellowship, University of Arizona, Tucson, AZ, USA
1987: Postdoctoral fellowship, Department of Biology, Animal Physiology, University of Osnabrück, DE

Activities in the Research System

Project coordination, membership in joint projects:

‐ Spokeswoman for the Board of Directors of the Hearing Research Center in Tübingen
‐ Spokesperson for the WMF joint project “Multimeric Ion Channel Complex” (Priority research program of the state of Baden-Württemberg)
‐ Speaker of the mini graduate school “Function and Pathophysiology of the Sensory Cells in the Inner Ear”, Eberhard Karls University of Tübingen, DE
‐ Coordinator of the IZKF doctoral college of the medical faculty of the Eberhard Karls University Tübingen
‐ Vice Speaker Neurosensory Center of the University of Tübingen (ZfN; Zentrum für Neurosensorik) (2011-2019)
‐ Member of the Association for Research in Otolaryngology (ARO)
‐ Member of the German Society for Otolaryngology, Head and Neck Surgery
‐ Member of the German Neuroscience Society
‐ Member of AcademiaNet
‐ Member Spitzenfrauen Gesundheit

Awards and conferred memberships

Since 2015: Member of the Leibniz Society of Sciences in Berlin
Since 2009: Member of the National Academy of Sciences Leopoldina

10 selected publications

  1. Marchetta P, Rüttiger L, Hobbs AJ, Singer W, Knipper M (2022) The role of cGMP signalling in auditory processing in health and disease. Br J Pharmacol. 179(11):2378-2393. DOI:10.1111/bph.15455 Open Access (conceptualization, writing of the manuscript)
  2. Marchetta P, Eckert P, Lukowski R, Ruth P, Singer W, Rüttiger L, Knipper M (2022) Loss of central mineralocorticoid or glucocorticoid receptors impacts auditory nerve processing in the cochlea. iScience. 25(3):103981. DOI:10.1016/j.isci.2022.103981 Open Access (conceptualization, methodology, investigation, writing - original draft, review editing)
  3. Knipper M, Singer W, Schwabe K, Hagberg GE, Li Hegner Y, Rüttiger L, Braun C, Land R (2022) Disturbed Balance of Inhibitory Signalling Links Hearing Loss and Cognition. Front Neural Circuits. 15:785603. DOI:10.3389/fncir.2021.785603 Open Access (design, writing and revision of the manuscript)
  4. Knipper M, Mazurek B, van Dijk P, Schulze H (2021) Too Blind to See the Elephant? Why Neuroscientists Ought to Be Interested in Tinnitus. J Assoc Res Otolaryngol. 22(6):609-621. DOI:10.1007/s10162-021-00815-1 Open Access (conceptualization, writing – original draft, revision and edition of the manuscript)
  5. Eckert P, Marchetta P, Manthey MK, Walter MH, Jovanovic S, Savitska D, Singer W, Jacob MH, Rüttiger L, Schimmang T, Milenkovic I, Pilz PKD, Knipper M (2021) Deletion of BDNF in Pax2 Lineage-Derived Interneuron Precursors in the Hindbrain Hampers the Proportion of Excitation/Inhibition, Learning, and Behavior. Front Mol Neurosci. 14:642679. DOI:10.3389/fnmol.2021.642679 Open Access (design, performed the research, writing – original draft, revision and edition of the manuscript)
  6. Knipper M, van Dijk P, Schulze H, Mazurek B, Krauss P, Scheper V, Warnecke A, Schlee W, Schwabe K, Singer W, Braun C, Delano PH, Fallgatter AJ, Ehlis AC, Searchfield GD, Munk MHJ, Baguley DM, Rüttiger L (2020) The Neural Bases of Tinnitus: Lessons from Deafness and Cochlear Implants. J Neurosci. 40(38):7190-7202. DOI:10.1523/JNEUROSCI.1314-19.2020 (design, performed the research, writing – original draft, revision and edition of the manuscript)
  7. Chumak T, Rüttiger L, Lee SC, Campanelli D, Zuccotti A, Singer W, Popelář J, Gutsche K, Geisler HS, Schraven SP, Jaumann M, Panford-Walsh R, Hu J, Schimmang T, Zimmermann U, Syka J, Knipper M (2016) BDNF in Lower Brain Parts Modifies Auditory Fiber Activity to Gain Fidelity but Increases the Risk for Generation of Central Noise After Injury. Mol Neurobiol. 53(8):5607-27. DOI:10.1007/s12035-015-9474-x Open Access (design, investigations, writing – original draft, writing- review/editing)
  8. Chen JT, Guo D, Campanelli D, Frattini F, Mayer F, Zhou L, Kuner R, Heppenstall PA, Knipper M, Hu J (2014) Presynaptic GABAergic inhibition regulated by BDNF contributes to neuropathic pain induction. Nat Commun. 5:5331. DOI:10.1038/ncomms6331 Open Access (performed immunofluorescence and molecular biological experiments)
  9. Jaumann M, Dettling J, Gubelt M, Zimmermann U, Gerling A, Paquet-Durand F, Feil S, Wolpert S, Franz C, Varakina K, Xiong H, Brandt N, Kuhn S, Geisler HS, Rohbock K, Ruth P, Schlossmann J, Hütter J, Sandner P, Feil R, Engel J, Knipper M, Rüttiger L (2012) cGMP-Prkg1 signaling and Pde5 inhibition shelter cochlear hair cells and hearing function. Nat Med. 18(2):252-9. DOI:10.1038/nm.2634 (design, conducted immunofluorescent microscopy and image analyses, planning and supervision of the project, writing and revision)
  10. Zuccotti A, Kuhn S, Johnson SL, Franz C, Singer W, Hecker D, Geisler HS, Köpschall I, Rohbock K, Gutsche K, Dlugaiszyk J, Schick B, Marcotti W, Rüttiger L, Schimmang T, Knipper M (2012) Lack of brain-derived neurotrophic factor hampers inner hair cell synapse physiology, but protects against noise-induced hearing loss. J Neurosci. 32(25):8545-53. DOI:10.1523/JNEUROSCI.1247-12.2012 (design, analysis and writing – original draft – review and editing)